BDBM52401 4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimethyl-aniline::4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimethylaniline::4-[2-(1,3-benzothiazol-2-yl)vinyl]-N,N-dimethylaniline::CHEMBL565657::MLS000573782::SMR000184633::[4-[(E)-2-(1,3-benzothiazol-2-yl)vinyl]phenyl]-dimethyl-amine::cid_5378081

SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1

InChI Key InChIKey=MVMOMSLTZMMLJR-FMIVXFBMSA-N

Data  1 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 52401   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataIC50:  2.04E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInsulin receptor(Homo sapiens (Human))
The Ohio State University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of thioflavin T from insulin receptor by thioflavin-T fluorescent dye assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)
Affinity DataIC50: >148nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay