BDBM5467 2-amino-6-(2-methyl)propyloxypurine::6-(2-methylpropoxy)-9H-purin-2-amine::O6-Substituted Guanine Deriv. 9

SMILES CC(C)COc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=RDPBSALYCFKBEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5467   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5467(6-(2-methylpropoxy)-9H-purin-2-amine | O6-Substitu...)
Affinity DataIC50: 4.20E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5467(6-(2-methylpropoxy)-9H-purin-2-amine | O6-Substitu...)
Affinity DataIC50: 4.50E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM5467(6-(2-methylpropoxy)-9H-purin-2-amine | O6-Substitu...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed