BDBM5490 2-Amino-6-(2-cyclohexyl)ethoxypurine::6-(2-cyclohexylethoxy)-9H-purin-2-amine::O6-Substituted Guanine Deriv. 30

SMILES Nc1nc(OCCC2CCCCC2)c2[nH]cnc2n1

InChI Key InChIKey=ZRURYXJTRCKFJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5490   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5490(6-(2-cyclohexylethoxy)-9H-purin-2-amine | 2-Amino-...)
Affinity DataIC50: 3.70E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM5490(6-(2-cyclohexylethoxy)-9H-purin-2-amine | 2-Amino-...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5490(6-(2-cyclohexylethoxy)-9H-purin-2-amine | 2-Amino-...)
Affinity DataIC50: 4.40E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed