BDBM63710 2-phenyl-1,3-thiazole-4-carboxylic acid::2-phenyl-4-thiazolecarboxylic acid::2-phenylthiazole-4-carboxylic acid::MLS000773831::SMR000364704::cid_138928

SMILES OC(=O)c1csc(n1)-c1ccccc1

InChI Key InChIKey=IBUSLNJQKLZPNR-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 63710   

TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM63710(2-phenyl-1,3-thiazole-4-carboxylic acid | 2-phenyl...)
Affinity DataKi:  1.90E+5nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM63710(2-phenyl-1,3-thiazole-4-carboxylic acid | 2-phenyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63710(2-phenyl-1,3-thiazole-4-carboxylic acid | 2-phenyl...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM63710(2-phenyl-1,3-thiazole-4-carboxylic acid | 2-phenyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed