BDBM75469 MLS000534075::N-cyclopentyl-2-benzo[e]benzofurancarboxamide::N-cyclopentylbenzo[e][1]benzofuran-2-carboxamide::N-cyclopentylbenzo[e]benzofuran-2-carboxamide::N-cyclopentylnaphtho[2,1-b]furan-2-carboxamide::SMR000141513::cid_749682

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3sccn23)cc1

InChI Key InChIKey=VPROQYQBNVRYST-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 75469   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 131nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75469BDBM75469(5-(4-acrylamidophenyl)-6-(4-((6-methylpyridin-2-yl...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent