BDBM75516 1-(5-chloranyl-1-methyl-indol-2-yl)carbonylpiperidine-4-carboxamide::1-(5-chloro-1-methyl-indole-2-carbonyl)isonipecotamide::1-(5-chloro-1-methylindole-2-carbonyl)piperidine-4-carboxamide::1-[(5-chloro-1-methyl-2-indolyl)-oxomethyl]-4-piperidinecarboxamide::MLS001183480::SMR000502071::cid_4619062

SMILES C=CC(=O)N1CC2(CC=C(c3c(-c4ccc(Oc5nccc(C)n5)cc4)c(C(N)=O)c4cnc(C)cn34)CC2)C1

InChI Key InChIKey=WXRPHKXAQDMYRJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75516   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75516BDBM75516(6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-meth...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75516BDBM75516(6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-meth...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75516BDBM75516(6-(2-acryloyl-2-azaspiro[3.5]non-6-en-7-yl)-3-meth...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent