BDBM7732 4-({[(3Z)-6-(hydroxymethyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}amino)benzene-1-sulfonamide::4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)amino]benzenesulfonamide::Oxindole-Based Inhibitor 68

SMILES NS(=O)(=O)c1ccc(cc1)N=CC1C(=O)Nc2cc(CO)ccc12

InChI Key InChIKey=LDTVCPBBOXODRG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7732   

TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7732(4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 61nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7732(4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 61nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7732(4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 61nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7732(4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 740nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM7732(4-[(6-Hydroxymethyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 740nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed