BDBM91846 Chk1_121

SMILES COc1cc(ccc1[N+]([O-])=O)-c1cc2Nc3ccc(CC(=O)Nc4ccc(cc4)N4CCOCC4)cc3NC(=O)c2cc1C

InChI Key InChIKey=UOXGORCNPCKCAX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 91846   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91846(Chk1_121)
Affinity DataKi:  63nMAssay Description:ChemBL affinity - Published Abbott papersMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91846(Chk1_121)
Affinity DataKi:  63nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1 [2-280](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM91846(Chk1_121)
Affinity DataKi:  64.4nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91846(Chk1_121)
Affinity DataIC50:  64nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In DepthDetails PubMed