BDBM91915 Chk1_49

SMILES OC1CCC(C1)Oc1ccc(Cl)cc1NC(=O)Nc1cnc(cn1)C#N

InChI Key InChIKey=QTKDJHMPFMGJMG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 91915   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91915(Chk1_49)
Affinity DataKi:  6nMAssay Description:ChemBL affinity - Published Abbott papersMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91915(Chk1_49)
Affinity DataKi:  6.30nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1 [2-280](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM91915(Chk1_49)
Affinity DataKi:  6.67nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csar

LigandPNGBDBM91915(Chk1_49)
Affinity DataIC50:  7nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In DepthDetails PubMed