Your request to link to rcsb for ALK4
- 1IAS: cytoplasmic domain of unphosphorylated type i tgf-beta receptor crystallized without fkbp12 (10.1016/S1097-2765(01)00332-X )
- 1PY5: crystal structure of tgf-beta receptor i kinase with inhibitor (10.1016/J.BMCL.2004.04.007 )
- 1RW8: crystal structure of tgf-beta receptor i kinase with atp site inhibitor (10.1016/J.BMCL.2004.04.007 )
- 1VJY: crystal structure of a naphthyridine inhibitor of human tgf- beta type i receptor (10.1021/JM0400247 )
- 2WOT: alk5 in complex with 4-((5,6-dimethyl-2-(2-pyridyl)-3-pyridyl)oxy)-n- (3,4,5-trimethoxyphenyl)pyridin-2-amine (10.1021/JM900807W )
- 2WOU: alk5 in complex with 4-((4-((2,6-dimethyl-3-pyridyl)oxy)-2-pyridyl) amino)benzenesulfonamide (10.1021/JM900807W )
- 2X7O: crystal structure of tgfbri complexed with an indolinone inhibitor (10.1021/JM100812A )
- 3FAA: crystal structure of tgfbri complexed with a 2-aminoimidazole inhibitor (10.1016/J.BMCL.2008.11.119 )
- 3GXL: alk-5 kinase complex with gw857175 (10.1016/J.BMCL.2009.02.087 )
- 3HMM: structure of alk5 + gw855857 (10.1016/J.BMCL.2009.02.087 )
- 3KCF: crystal structure of tgfbri complexed with a pyrazolone inhibitor (10.1016/J.BMCL.2009.10.108 )
- 3TZM: tgf-beta receptor type 1 in complex with sb431542 (10.1016/J.CELLSIG.2011.09.027 )
- 4X0M: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 4X2F: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 4X2G: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 4X2J: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 4X2K: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 4X2N: selection of fragments for kinase inhibitor design: decoration is key (10.1021/JM501597J )
- 5E8S: tgf-beta receptor type 1 kinase domain (wt) (10.1107/S2059798316003624 )
- 5E8T: tgf-beta receptor type 1 kinase domain (t204d) (10.1107/S2059798316003624 )
- 5E8U: tgf-beta receptor type 1 kinase domain (t204d,i211v,y249f,s280t, y282f,s287n,a350c,l352f) (10.1107/S2059798316003624 )
- 5E8W: tgf-beta receptor type 1 kinase domain (t204d) in complex with staurosporine (10.1107/S2059798316003624 )
- 5E8X: tgf-beta receptor type 1 kinase domain (t204d,i211v,y249f,s280t, y282f,s287n,a350c,l352f) in complex with staurosporine (10.1107/S2059798316003624 )
- 5E8Z: tgf-beta receptor type 1 kinase domain (t204d) in complex with 3- amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3- yl]pyrazine-2-carboxamide (10.1107/S2059798316003624 )
- 5E90: tgf-beta receptor type 1 kinase domain (t204d,i211v,y249f, s280t, y282f,s287n,a350c,l352f) in complex with 3-amino-6- [4-(2- hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2- carboxamide (10.1107/S2059798316003624 )
- 5FRI: alk5 in complex witha an n-(4-anilino-2-pyridyl)acetamide inhibitor. (10.1039/C6MD00039H )
- 5QIK: tgf-beta receptor type 1 kinase domain (t204d) in complex with n-{4- [3-(6-fluoropyridin-3-yl)-4-oxo-4,5,6,7-tetrahydro-1h-pyrrolo[3,2- c]pyridin-2-yl]pyridin-2-yl}acetamide (10.1021/ACSMEDCHEMLETT.8B00357 )
- 5QIL: tgf-beta receptor type 1 kinase domain (t204d) in complex with n-{4- [3-(6-methoxypyridin-3-yl)-1h-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2- yl}acetamide (10.1021/ACSMEDCHEMLETT.8B00357 )
- 5QIM: tgf-beta receptor type 1 kinase domain (t204d) in complex with n-{4- [3-(5-methoxypyridin-2-yl)-1h-pyrrolo[3,2-b] pyridin-2-yl]pyridin-2- yl}acetamide (10.1021/ACSMEDCHEMLETT.8B00357 )
- 5QTZ: tgf-beta receptor type 1 kinase domain (t204d) in complex with 6-[1- (2,2-difluoroethyl)-4-(6-methylpyridin-2-yl)-1h-imidazol-5- yl]imidazo[1,2-a]pyridine (10.1021/ACSMEDCHEMLETT.9B00552 )
- 5QU0: tgf-beta receptor type 1 kinase domain (t204d) in complex with 6-[4- (3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1h-imidazol-5- yl]imidazo[1,2-b]pyridazine-3-carbonitrile (10.1021/ACSMEDCHEMLETT.9B00552 )
- 5USQ: alk-5 kinase inhibitor complex (10.1016/J.BMCL.2017.03.026 )
- 6B8Y: tgf-beta receptor type 1 kinase domain (t204d) in complex with n-(3- fluoropyridin-4-yl)-2-[6-(trifluoromethyl)pyridin-2-yl]-7h-pyrrolo[2, 3-d]pyrimidin-4-amine (10.1016/J.BMC.2018.01.014 )