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Found 3991 with Last Name = 'hong' and Initial = 'v'
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKi:  0.129nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to human neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509512(CHEMBL4579623)
Affinity DataKi:  0.510nMAssay Description:Binding affinity to human neurotensin receptor 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKi:  0.741nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509515(CHEMBL4463399)
Affinity DataKi:  0.759nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509508(CHEMBL4534768)
Affinity DataKi:  0.955nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509515(CHEMBL4463399)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509513(CHEMBL4537266)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509513(CHEMBL4537266)
Affinity DataKi:  2nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509508(CHEMBL4534768)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509514(CHEMBL4584647)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509508(CHEMBL4534768)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509516(CHEMBL4592541)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509513(CHEMBL4537266)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509509(CHEMBL4566971)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  4nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509514(CHEMBL4584647)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509510(CHEMBL4564746)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509516(CHEMBL4592541)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59098(Bi-ligand, 1)
Affinity DataKi:  26nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59099(Bi-ligand, 2)
Affinity DataKi:  42nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmin(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  61nMAssay Description:Binding affinity at Grp94 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59101(Bi-ligand, 4)
Affinity DataKi:  100nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataKi:  202nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  255nMAssay Description:Binding affinity at TRAP1 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59101(Bi-ligand, 4)
Affinity DataKi:  620nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59101(Bi-ligand, 4)
Affinity DataKi:  7.90E+3nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59099(Bi-ligand, 2)
Affinity DataKi:  1.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataKi:  1.20E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataKi: >2.50E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59098(Bi-ligand, 1)
Affinity DataKi: >5.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59099(Bi-ligand, 2)
Affinity DataKi: >5.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics

LigandPNGBDBM59098(Bi-ligand, 1)
Affinity DataKi:  5.50E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451322(CHEMBL4210026)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451338(CHEMBL4207673)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451337(CHEMBL4204601)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401335(CHEMBL2205798)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50572947(CHEMBL4871014)
Affinity DataIC50:  1nMAssay Description:Inhibition of human ATX assessed as reduction in LPA formation using FS-3 as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451325(CHEMBL4202424)
Affinity DataIC50:  1nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042864(CHEMBL3354514)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401336(CHEMBL2205245)
Affinity DataIC50:  1nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042871(CHEMBL3354521)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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