TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 7.55E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Binding affinity to GST-tagged 14-3-3-zeta (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS40...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+4nMAssay Description:Binding affinity to GST-tagged 14-3-3-gamma (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS4...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia
Curated by ChEMBL
University Of Pavia
Curated by ChEMBL
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia
Curated by ChEMBL
University Of Pavia
Curated by ChEMBL
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia
Curated by ChEMBL
University Of Pavia
Curated by ChEMBL
Affinity DataIC50: 3.84E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia
Curated by ChEMBL
University Of Pavia
Curated by ChEMBL
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
Affinity DataKd: 41nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.14E+3nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 370nMAssay Description:Binding affinity to recombinant human His-tagged 14-3-3zeta expressed in Escherichia coli K12 by ITC methodMore data for this Ligand-Target Pair