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Found 34 with Last Name = 'karawajczyk' and Initial = 'a'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205604(CHEMBL3907401)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205613(CHEMBL3934464)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205599(CHEMBL3933197)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205619(CHEMBL3965269)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205603(CHEMBL3937306)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205600(CHEMBL3897315)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205614(CHEMBL3892849)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205610(CHEMBL3926566)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205602(CHEMBL3919202)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205611(CHEMBL3969575)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205608(CHEMBL3898376)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM14769(6-(3,4-Dimethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205617(CHEMBL3916376)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462078(CHEMBL4243744)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462085(CHEMBL4240436)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462080(CHEMBL4250552)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462083(CHEMBL4237531)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein sigma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462084(CHEMBL4247540)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205609(CHEMBL3938207)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205605(CHEMBL3932749)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205618(CHEMBL3929714)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205601(CHEMBL3892468)
Affinity DataIC50:  4.17E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205607(CHEMBL3925358)
Affinity DataIC50:  7.55E+3nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  9.30E+3nMAssay Description:Binding affinity to GST-tagged 14-3-3-zeta (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS40...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205612(CHEMBL3910284)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein gamma(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  1.64E+4nMAssay Description:Binding affinity to GST-tagged 14-3-3-gamma (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50205606(CHEMBL3945980)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50526290(CHEMBL4555346)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50526292(CHEMBL4460312)
Affinity DataIC50:  2.84E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50526293(CHEMBL4541812)
Affinity DataIC50:  3.84E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAutoinducer-2 kinase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50526291(CHEMBL4443015)
Affinity DataIC50:  4.75E+5nMAssay Description:Inhibition of Salmonella typhimurium LsrK expressed in Escherichia coli MET1158 using (S)-DPD as substrate after 15 mins by Kinase Glo luminescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462079(CHEMBL4247970)
Affinity DataKd:  41nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462082(CHEMBL4245176)
Affinity DataKd:  1.14E+3nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50462081(CHEMBL4243245)
Affinity DataKd:  370nMAssay Description:Binding affinity to recombinant human His-tagged 14-3-3zeta expressed in Escherichia coli K12 by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed