Ligand Info
Affinity DataKi: 1.80nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [125I]Angiotensin 4 from human recombinant IRAP expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of recombinant human IRAP expressed in GnT1 deficient HEK293S cells using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 m...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidaseMore data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of IRAP in HEKT cells assessed as hydrolysis of L-leucine-4-methyl-7-coumarinylamide after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 30.4nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 41.1nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibitory activity against Leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 62.4nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 64.2nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 177nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 196nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 242nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 282nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair