TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataIC50: 25.1nMAssay Description:In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataIC50: 100nMAssay Description:In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of GST-tagged recombinant human VEGFR (789-end) expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins followed by ATP...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataIC50: 251nMAssay Description:In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 276nMAssay Description:Inhibition of GST-tagged recombinant human VEGFR (789-end) expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins followed by ATP...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataIC50: 398nMAssay Description:In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair