Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit epsilon/Serine/threonine-protein kinase TBK1'
LigandPNGBDBM50520150(CHEMBL4566796)
Affinity DataIC50:  63nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520165(CHEMBL4454902)
Affinity DataIC50:  66nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520151(CHEMBL4537673)
Affinity DataIC50:  74nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520157(CHEMBL4436188)
Affinity DataIC50:  93nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520159(CHEMBL4543618)
Affinity DataIC50:  119nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520142(CHEMBL4435393)
Affinity DataIC50:  131nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520148(CHEMBL4538751 | US10894784, Example 30.03.01.A)
Affinity DataIC50:  140nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520158(CHEMBL4453292 | US10894784, Example 143.02)
Affinity DataIC50:  213nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520161(CHEMBL4468020 | US10894784, Example 39.01.02)
Affinity DataIC50:  368nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520155(CHEMBL4552254 | US10894784, Example 30.01.01)
Affinity DataIC50:  773nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520160(CHEMBL4515413 | US10894784, Example 01.03)
Affinity DataIC50:  840nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520174(CHEMBL4553949 | US10894784, Example 16.06.02.A)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520175(CHEMBL4451595 | US10894784, Example 135.02)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520162(CHEMBL4453481 | US10894784, Example 38.02)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520147(CHEMBL4436416 | US10894784, Example 37.01)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520152(CHEMBL4594167 | US10894784, Example 150.02)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520145(CHEMBL4459120)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520143(CHEMBL4455930)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520168(CHEMBL4549459 | US10894784, Example 16.01.02)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520156(CHEMBL4577511 | US10894784, Example 16.06.02.B)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520173(CHEMBL4538591 | US10894784, Example 179.02)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520166(CHEMBL4587843)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520153(CHEMBL4566710)
Affinity DataIC50:  5.16E+3nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520163(CHEMBL4524534)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520176(CHEMBL4438389)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
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LigandPNGBDBM50520154(CHEMBL4466150 | US10894784, Example 17.02)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed