Found 30 of ic50 for monomerid = 16173 TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences
Curated by ChEMBL
Parion Sciences
Curated by ChEMBL
Affinity DataIC50: 776nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 781nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
3D Structure (crystal)TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.63E+3nMAssay Description:The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.88E+3nMpH: 7.2 T: 2°CAssay Description:The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of urokinase-type plasminogen activator using Glt-Gly-Arg-AMC as substrate by spectrofluorometryMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human uPA using pyro-Glu-Gly-Arg-pNA as substrate assessed as para-nitroaniline release from substrate measured for 5 mins by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of tissue-type plasminogen activator (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of ASIC1 in Sprague-Dawley rat articular chondrocytes assessed as decrease in acid-induced intracellular calcium level by Fluo-3AM dye bas...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of factor Xa (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of activated protein C (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protoc...More data for this Ligand-Target Pair
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of platelet NHE1 in human platelet rich plasma assessed as decrease in platelet swelling preincubated for 3 mins followed by sodium propio...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibitory activity of the compound was tested against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong
Curated by ChEMBL
University Of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of tPA using CH3SO2-D-HHT-Gly-Arg-pNA as substrate by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of plasmin using tosyl-Gly-Pro-Lys-pNA as substrate by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
