Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human ACE using Mca-BK2 as substrate preincubated for 10 mins followed by fluorogenic substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human fully glycosylated ACE C-terminal domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human fully glycosylated ACE N-terminal domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of rat kidney NEP using dansyl-Gly-Phe-Arg as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against purified rat kidney neutral endopeptidase (NEP) using a fluorometric assay with dansyl-Gly-Phe-Arg as the substr...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of APP (unknown origin)More data for this Ligand-Target Pair