TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of wild type ROS1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Inhibition of wild type human recombinant ALK kinase domain (amino acids 1093 to 1141) expressed in baculovirus system using 5'FAM-KKSRGDYMTMQIG-CONH...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Inhibition of ROS1 L2026M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of human recombinant ALK L1196M mutant kinase domain (amino acids 1093 to 1141) expressed in baculovirus system using 5'FAM-KKSRGDYMTMQIG-...More data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibition of ROS1 G2032R mutant (unknown origin)More data for this Ligand-Target Pair