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Found 2 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50459709'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataKi:  7.90nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50459709(CHEMBL4209052 | US10836764, Compound 137)
Affinity DataEC50:  12nMAssay Description:Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed