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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM328389'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328389(3-(difluoromethyl)-6-fluoro-1-((4-methoxy-3-(piper...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328389(3-(difluoromethyl)-6-fluoro-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  0.260nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328389(3-(difluoromethyl)-6-fluoro-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  7.10nMAssay Description:Antagonist activity at recombinant human 5HT6R expressed in CHO cells assessed as inhibition of 5HT-stimulated cAMP accumulation incubated for 4 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed