Affinity DataIC50: 21nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat acid ceramidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:Inhibition of acid ceramidase in human G361 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair