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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50005021'
TargetBeta-secretase 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005021(CHEMBL2408786 | US9650336, Example 3)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as release of sAPPbeta after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005021(CHEMBL2408786 | US9650336, Example 3)
Affinity DataIC50:  18nMAssay Description:Inhibition of human BACE1 cloned in HEK293 cells using Eu-CEVNLDAEFK-QSY 7 as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed