Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM50271172'
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50271172(CHEMBL4127711)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50271172(CHEMBL4127711)
Affinity DataKi:  1nMAssay Description:Inhibition of human BACE2 preincubated for 30 mins followed by QSY7- EISEVNLDAEFC-Eu-amide substrate addition and measured after 1.5 hrs by HTRF assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50271172(CHEMBL4127711)
Affinity DataKi:  1nMAssay Description:Binding affinity to human autoBACE2 using QSY7-APPswe-Eu as substrate preincubated for 30 mins followed by substrate addition measured after 90 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed