Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50427065'
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL5/RANTES-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL15/Leukotactin1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL23/CKbeta8.1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3/MIP-1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL15/Leukotactin1-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  5.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3/MIP-1alpha-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]-CCL15/Leukotactin1 from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]-CCL15/Leukotactin1 from CCR1 in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at CCR1 in human monocytes assessed as inhibition of CCL15/Leukotactin1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Mus musculus)
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at CCR1 in mouse WEHI274.1 cells assessed as inhibition of CCL3/MIP-1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Mus musculus)
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427065(CHEMBL2322875)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in mouse WEHI274.1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed