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Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM476382'
Target
Coagulation factor XII
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM476382
(1,2,3,4-tetrahydroisoquinolin-6-yl (3S)-4-(N,3-dic...)
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Affinity Data
IC50: 18.7nM
Assay Description:
The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...
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Target Info
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Ligand Info
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US Patent
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