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Enz. Inhib. hit(s) with Target = 'Coagulation factor XII' and Ligand = 'BDBM476488'
Target
Coagulation factor XII
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM476488
((2S)-1-(N2-cyclohexyl-N6,N6- dimethyl-D-lysyl)-4-(...)
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Affinity Data
IC50: 29.7nM
Assay Description:
The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...
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Target Info
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Ligand Info
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US Patent
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