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Found 2 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM474708'
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474708(US10849883, Compound 132g)
Affinity DataIC50:  650nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474708(US10849883, Compound 132g)
Affinity DataIC50: <1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent