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Found 4 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM161389'
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)
Affinity DataIC50:  0.5nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)
Affinity DataIC50:  0.5nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed