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Found 3 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-9' and Ligand = 'BDBM50277889'
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  69nMAssay Description:Inhibition of human 20S immunoproteasome beta-1i subunit using (Ac-PAL)2R110 as substrate preincubated for 2 hrs followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of 20S proteasome beta 1i (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank