Found 7 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-4' and Ligand = 'BDBM5446'
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Erbb4More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMpH: 7.5Assay Description:The EGFR, HER2 and HER4 kinase assay were performed using radiolabeled [gamma-32P] ATP from GE Healthcare. More data for this Ligand-Target Pair
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding constant for ERBB4 kinase domainMore data for this Ligand-Target Pair