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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM476337'
TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent