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Found
1
Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM484436'
Target
SH2B adapter protein 2
(Human)
Novartis
US Patent
Ligand
BDBM484436
(US10934285, Example 20)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...
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