Found 6 Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM85507' TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 289nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 289nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 289nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 1.30E+5nMAssay Description:Binding affinity to TTR in human plasma assessed as protein stabilization preincubated for 1 hr followed by urea-mediated denaturation by Western blo...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataKd: 592nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataKd: 260nMAssay Description:Binding affinity to TTR (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
