Found 172 of ic50 for monomerid = 50439674 
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HADC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC6 using (Z-(Ac)Lys-AMC) as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition and shaken for 60 secsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate and trypsin addition by microplate reader ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 6 mins followed by substrate addition measured after 60 secsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate pre-incubated with compound for 10 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using FTS as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition and shaken for 60 secs and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using Boc-Lys-(Ac)-AMC as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Anhui University Of Chinese Medicine
Curated by ChEMBL
Anhui University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC1 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC6 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Anhui University Of Chinese Medicine
Curated by ChEMBL
Anhui University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HDAC6 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC6 (unknown origin) using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus in...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Anhui University Of Chinese Medicine
Curated by ChEMBL
Anhui University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-tagged HDAC2 expressed in Sf9 cells using FTS as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of full length recombinant human C-terminal GST-tagged HDAC2 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of HADC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 cells using FTS as substrate preincubated for 10 mins followed by substrate addition and shaken for 60 sec...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 insect cells using FTS as substrate preincubated for 10 mins followed by substrate addition and shaken for...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
