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Compile Data Set for Download or QSAR

Found 782 hits of ic50 for UniProtKB: P08908   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50212607
PNG
(CHEMBL57330)
Show SMILES CCCN(CCCCNC(=O)c1cc(=O)oc2c3CCCN4CCCc(cc12)c34)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C33H41N3O5/c1-3-14-35(23-19-27-28(39-2)11-6-12-29(27)40-21-23)15-5-4-13-34-33(38)26-20-30(37)41-32-24-10-8-17-36-16-7-9-22(31(24)36)18-25(26)32/h6,11-12,18,20,23H,3-5,7-10,13-17,19,21H2,1-2H3,(H,34,38)
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n/an/a 0n/an/an/an/an/an/a


TBA

Assay Description
The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranes


Citation and Details

BindingDB Entry DOI: 10.7270/Q27D2X8F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50036844
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)c2ccccc2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H30N2O4/c1-3-13-26(18-16-21-22(30-2)11-8-12-23(21)31-17-18)14-6-7-15-27-24(28)19-9-4-5-10-20(19)25(27)29/h4-5,8-12,18H,3,6-7,13-17H2,1-2H3
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TBA

Assay Description
The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranes


Citation and Details

BindingDB Entry DOI: 10.7270/Q27D2X8F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM82368
PNG
(CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C26H38N2O4/c1-3-13-27(20-16-21-22(31-2)9-8-10-23(21)32-19-20)14-6-7-15-28-24(29)17-26(18-25(28)30)11-4-5-12-26/h8-10,20H,3-7,11-19H2,1-2H3
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TBA

Assay Description
The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranes


Citation and Details

BindingDB Entry DOI: 10.7270/Q27D2X8F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50036868
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)c2ccccc2S1(=O)=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H30N2O5S/c1-3-13-25(18-16-20-21(30-2)10-8-11-22(20)31-17-18)14-6-7-15-26-24(27)19-9-4-5-12-23(19)32(26,28)29/h4-5,8-12,18H,3,6-7,13-17H2,1-2H3
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TBA

Assay Description
The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranes


Citation and Details

BindingDB Entry DOI: 10.7270/Q27D2X8F
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50212622
PNG
(CHEMBL57187)
Show SMILES CCCN(CCCCNc1ccc([N+]([O-])=O)c2nonc12)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C23H29N5O5/c1-3-12-27(16-14-17-20(31-2)7-6-8-21(17)32-15-16)13-5-4-11-24-18-9-10-19(28(29)30)23-22(18)25-33-26-23/h6-10,16,24H,3-5,11-15H2,1-2H3
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n/an/a 0n/an/an/an/an/an/a


TBA

Assay Description
The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranes


Citation and Details

BindingDB Entry DOI: 10.7270/Q27D2X8F
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224302
PNG
(CHEMBL31783)
Show SMILES CSc1ccc2[nH]cc(CCN(C)C)c2c1
Show InChI InChI=1S/C13H18N2S/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
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n/an/a 0.00000100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224300
PNG
(CHEMBL352315)
Show SMILES CC(C)N(CCc1c[nH]c2ccc3OCOc3c12)C(C)C
Show InChI InChI=1S/C17H24N2O2/c1-11(2)19(12(3)4)8-7-13-9-18-14-5-6-15-17(16(13)14)21-10-20-15/h5-6,9,11-12,18H,7-8,10H2,1-4H3
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n/an/a 0.00000200n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224303
PNG
(CHEMBL283686)
Show SMILES CN(C)CCc1c[nH]c2cc3OCOc3cc12
Show InChI InChI=1S/C13H16N2O2/c1-15(2)4-3-9-7-14-11-6-13-12(5-10(9)11)16-8-17-13/h5-7,14H,3-4,8H2,1-2H3
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n/an/a 0.0000410n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224301
PNG
(CHEMBL417480)
Show SMILES CSc1ccc2c(CCN(C)C)c[nH]c2c1
Show InChI InChI=1S/C13H18N2S/c1-15(2)7-6-10-9-14-13-8-11(16-3)4-5-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
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n/an/a 0.0000410n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224305
PNG
(CHEMBL285355)
Show SMILES CSc1cccc2[nH]cc(CCN(C)C)c12
Show InChI InChI=1S/C13H18N2S/c1-15(2)8-7-10-9-14-11-5-4-6-12(16-3)13(10)11/h4-6,9,14H,7-8H2,1-3H3
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n/an/a 0.000151n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50224304
PNG
(CHEMBL368261)
Show SMILES CC(C)N(CCc1c[nH]c2cc3OCOc3cc12)C(C)C
Show InChI InChI=1S/C17H24N2O2/c1-11(2)19(12(3)4)6-5-13-9-18-15-8-17-16(7-14(13)15)20-10-21-17/h7-9,11-12,18H,5-6,10H2,1-4H3
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n/an/a 0.000933n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand


J Med Chem 25: 908-13 (1982)


Article DOI: 10.1021/jm00350a005
BindingDB Entry DOI: 10.7270/Q2H70J1R
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466559
PNG
(US10800755, Example 14)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H27F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,7,17H,5-6,8-14H2,1H3,(H,23,26)
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US Patent
n/an/a 0.100n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50421373
PNG
(CHEMBL416523)
Show SMILES COc1cccc2OCC(CNCCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C24H34N2O4/c1-29-20-7-6-8-21-19(20)13-18(17-30-21)16-25-11-4-5-12-26-22(27)14-24(15-23(26)28)9-2-3-10-24/h6-8,18,25H,2-5,9-17H2,1H3
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n/an/a 0.129n/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by displacement of [3H]8-OH-DPAT.


Citation and Details

Article DOI: 10.1016/0960-894X(96)00174-6
BindingDB Entry DOI: 10.7270/Q2X92CK1
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM82368
PNG
(CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C26H38N2O4/c1-3-13-27(20-16-21-22(31-2)9-8-10-23(21)32-19-20)14-6-7-15-28-24(29)17-26(18-25(28)30)11-4-5-12-26/h8-10,20H,3-7,11-19H2,1-2H3
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TBA

Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by displacement of [3H]8-OH-DPAT.


Citation and Details

Article DOI: 10.1016/0960-894X(96)00174-6
BindingDB Entry DOI: 10.7270/Q2X92CK1
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064582
PNG
(6-{2-[4-(2-Hydroxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3O)cc2sc1=O
Show InChI InChI=1S/C20H23N3O2S/c1-21-17-7-6-15(14-19(17)26-20(21)25)8-9-22-10-12-23(13-11-22)16-4-2-3-5-18(16)24/h2-7,14,24H,8-13H2,1H3
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n/an/a 0.200n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064578
PNG
(6-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCc2ccc3[nH]c(=O)sc3c2)CC1
Show InChI InChI=1S/C22H27N3O2S/c1-27-20-8-3-2-7-19(20)25-14-12-24(13-15-25)11-5-4-6-17-9-10-18-21(16-17)28-22(26)23-18/h2-3,7-10,16H,4-6,11-15H2,1H3,(H,23,26)
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n/an/a 0.200n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466556
PNG
(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H24F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,6,15H,4-5,7-13H2,(H,26,29)
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US Patent
n/an/a 0.200n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50151982
PNG
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)
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n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT1A expressed in CHO cell membranes assessed as increase in [35S]-GTPgammaS binding after 30 mins by liquid scintillation...


J Med Chem 61: 5822-5880 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01788
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064576
PNG
(7-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCc2ccc3N(C)C(=O)COc3c2)CC1
Show InChI InChI=1S/C22H27N3O3/c1-23-18-8-7-17(15-21(18)28-16-22(23)26)9-10-24-11-13-25(14-12-24)19-5-3-4-6-20(19)27-2/h3-8,15H,9-14,16H2,1-2H3
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n/an/a 0.200n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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n/an/a 0.280n/an/an/an/an/an/a



National University of Ireland Galway

Curated by ChEMBL


Assay Description
Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter method


Eur J Med Chem 176: 292-309 (2019)


Article DOI: 10.1016/j.ejmech.2019.04.064
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466577
PNG
(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H24F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-7H,8-12H2,1-3H3,(H,22,25)
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US Patent
n/an/a 0.300n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064587
PNG
(6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCc2ccc3[nH]c(=O)sc3c2)CC1
Show InChI InChI=1S/C20H23N3O2S/c1-25-18-5-3-2-4-17(18)23-12-10-22(11-13-23)9-8-15-6-7-16-19(14-15)26-20(24)21-16/h2-7,14H,8-13H2,1H3,(H,21,24)
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n/an/a 0.300n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM21392
PNG
(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Show SMILES NCCc1c[nH]c2ccc(cc12)C(N)=O
Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)
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n/an/a 0.300n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In Vitro Binding affinity againist 5-HT1A receptor by displacing [3H]8-OH-DPAT from pig cortex


Bioorg Med Chem Lett 4: 1207-1212 (1994)


Article DOI: 10.1016/S0960-894X(01)80331-0
BindingDB Entry DOI: 10.7270/Q2TH8P0J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50403509
PNG
(CHEMBL89007)
Show SMILES Clc1ccc(NCCCNCC2CCc3ccccc3O2)nn1
Show InChI InChI=1S/C17H21ClN4O/c18-16-8-9-17(22-21-16)20-11-3-10-19-12-14-7-6-13-4-1-2-5-15(13)23-14/h1-2,4-5,8-9,14,19H,3,6-7,10-12H2,(H,20,22)
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n/an/a 0.398n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to bind to 5-hydroxytryptamine 1A receptor from cloned human expressed in Ha7 cells


Bioorg Med Chem Lett 5: 2649-2654 (1995)


Article DOI: 10.1016/0960-894X(95)00473-7
BindingDB Entry DOI: 10.7270/Q20Z74GV
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466547
PNG
(US10800755, Example 4)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H29F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,16-17H,5-14H2,1H3,(H,23,26)
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US Patent
n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466575
PNG
(N-[2-(6-Methyl-3′,6′-dihydro[2,4′...)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H27N3O2/c1-15-3-2-4-18(21-15)16-5-10-22(11-6-16)12-9-20-19(23)17-7-13-24-14-8-17/h2-5,17H,6-14H2,1H3,(H,20,23)
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n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466535
PNG
(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H26F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,14-15H,4-13H2,(H,26,29)
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n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM392076
PNG
(US10301272, Example 7/9)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N[C@H]2C[C@@H](C2)C(O)=O)c2ccccc12
Show InChI InChI=1S/C30H37N3O5S2/c1-30(2,3)33-40(37,38)25-14-13-23(21-11-7-8-12-22(21)25)26-24(15-18-9-5-4-6-10-18)32-28(39-26)27(34)31-20-16-19(17-20)29(35)36/h7-8,11-14,18-20,33H,4-6,9-10,15-17H2,1-3H3,(H,31,34)(H,35,36)/t19-,20-
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n/an/a 0.430n/an/an/an/an/an/a



Phenex Pharmaceuticals AG

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor after 60 mins by scintillation counting analysis


Bioorg Med Chem Lett 28: 1446-1455 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.093
BindingDB Entry DOI: 10.7270/Q27W6FPC
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064584
PNG
(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Show SMILES CN1C(=O)COc2cc(CCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)ccc12
Show InChI InChI=1S/C24H28F3N3O2/c1-28-21-9-8-18(15-22(21)32-17-23(28)31)5-2-3-10-29-11-13-30(14-12-29)20-7-4-6-19(16-20)24(25,26)27/h4,6-9,15-16H,2-3,5,10-14,17H2,1H3
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n/an/a 0.600n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50520683
PNG
(CHEMBL4476621)
Show SMILES Oc1ccccc1C(=O)NNC(=S)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H11Cl2N3O2S/c15-10-6-5-8(7-11(10)16)17-14(22)19-18-13(21)9-3-1-2-4-12(9)20/h1-7,20H,(H,18,21)(H2,17,19,22)
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n/an/a 0.600n/an/an/an/an/an/a



Universit£ Catholique de Louvain (UCLouvain)

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor after 60 mins by scintillation counting analysis


Eur J Med Chem 159: 324-338 (2018)


Article DOI: 10.1016/j.ejmech.2018.09.067
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064574
PNG
(4-Methyl-7-{2-[4-(3-trifluoromethyl-phenyl)-pipera...)
Show SMILES CN1C(=O)COc2cc(CCN3CCN(CC3)c3cccc(c3)C(F)(F)F)ccc12
Show InChI InChI=1S/C22H24F3N3O2/c1-26-19-6-5-16(13-20(19)30-15-21(26)29)7-8-27-9-11-28(12-10-27)18-4-2-3-17(14-18)22(23,24)25/h2-6,13-14H,7-12,15H2,1H3
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n/an/a 0.700n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064572
PNG
(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O
Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3
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n/an/a 0.700n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064585
PNG
(6-{2-[4-(2-Hydroxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES Oc1ccccc1N1CCN(CCc2ccc3[nH]c(=O)sc3c2)CC1
Show InChI InChI=1S/C19H21N3O2S/c23-17-4-2-1-3-16(17)22-11-9-21(10-12-22)8-7-14-5-6-15-18(13-14)25-19(24)20-15/h1-6,13,23H,7-12H2,(H,20,24)
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n/an/a 0.700n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50152022
PNG
(3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-buty...)
Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCOc4c3)c2c1
Show InChI InChI=1S/C24H26N4O2/c25-15-18-4-6-22-21(13-18)19(16-26-22)3-1-2-8-27-9-11-28(12-10-27)20-5-7-23-24(14-20)30-17-29-23/h4-7,13-14,16,26H,1-3,8-12,17H2
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT1A expressed in CHO cell membranes assessed as increase in [35S]-GTPgammaS binding after 30 mins by liquid scintillation...


J Med Chem 61: 5822-5880 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01788
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50084855
PNG
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Show SMILES Oc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C24H32N4O2/c29-22-11-5-4-10-21(22)27-17-14-26(15-18-27)16-19-28(23-12-6-7-13-25-23)24(30)20-8-2-1-3-9-20/h4-7,10-13,20,29H,1-3,8-9,14-19H2
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n/an/a 0.770n/an/an/an/an/an/a



VU University Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation counting


J Med Chem 54: 3480-91 (2011)


Article DOI: 10.1021/jm1009956
BindingDB Entry DOI: 10.7270/Q2HX1D1C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50084855
PNG
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Show SMILES Oc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C24H32N4O2/c29-22-11-5-4-10-21(22)27-17-14-26(15-18-27)16-19-28(23-12-6-7-13-25-23)24(30)20-8-2-1-3-9-20/h4-7,10-13,20,29H,1-3,8-9,14-19H2
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n/an/a 0.770n/an/an/an/an/an/a



VU University Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation counting


Eur J Med Chem 46: 5728-35 (2011)


Article DOI: 10.1016/j.ejmech.2011.06.023
BindingDB Entry DOI: 10.7270/Q2542P0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466565
PNG
(US10800755, Example 19)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H24F3N3O2/c20-19(21,22)17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-4,15H,5-13H2,(H,23,26)
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n/an/a 0.800n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50002173
PNG
(3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...)
Show SMILES Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2
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n/an/a 0.800n/an/an/an/an/an/a



University of Li£ge

Curated by ChEMBL


Assay Description
Inhibition of 5HT1A receptor


Bioorg Med Chem Lett 20: 1118-23 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.027
BindingDB Entry DOI: 10.7270/Q2TH8MTG
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064577
PNG
(7-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCc2ccc3N(C)C(=O)COc3c2)CC1
Show InChI InChI=1S/C24H31N3O3/c1-25-20-11-10-19(17-23(20)30-18-24(25)28)7-5-6-12-26-13-15-27(16-14-26)21-8-3-4-9-22(21)29-2/h3-4,8-11,17H,5-7,12-16,18H2,1-2H3
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n/an/a 0.800n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064589
PNG
(6-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCc2ccc3n(C)c(=O)sc3c2)CC1
Show InChI InChI=1S/C23H29N3O2S/c1-24-20-11-10-18(17-22(20)29-23(24)27)7-5-6-12-25-13-15-26(16-14-25)19-8-3-4-9-21(19)28-2/h3-4,8-11,17H,5-7,12-16H2,1-2H3
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n/an/a 0.800n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
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n/an/a 0.910n/an/an/an/an/an/a



VU University Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation counting


J Med Chem 54: 3480-91 (2011)


Article DOI: 10.1021/jm1009956
BindingDB Entry DOI: 10.7270/Q2HX1D1C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
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n/an/a 0.910n/an/an/an/an/an/a



VU University Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation counting


Eur J Med Chem 46: 5728-35 (2011)


Article DOI: 10.1016/j.ejmech.2011.06.023
BindingDB Entry DOI: 10.7270/Q2542P0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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0.650n/a 0.970n/an/an/an/an/an/a



Reviva Pharmaceuticals Inc

US Patent


Assay Description
Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...


US Patent US9604944 (2017)


BindingDB Entry DOI: 10.7270/Q2ZW1NZ2
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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n/an/a 0.970n/an/an/an/an/an/a



Reviva Pharmaceuticals Inc

US Patent


Assay Description
Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...


US Patent US9975862 (2018)


BindingDB Entry DOI: 10.7270/Q2QZ2D9J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50064586
PNG
(3-Methyl-6-{2-[4-(3-trifluoromethyl-phenyl)-pipera...)
Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3cccc(c3)C(F)(F)F)cc2sc1=O
Show InChI InChI=1S/C21H22F3N3OS/c1-25-18-6-5-15(13-19(18)29-20(25)28)7-8-26-9-11-27(12-10-26)17-4-2-3-16(14-17)21(22,23)24/h2-6,13-14H,7-12H2,1H3
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n/an/a 1n/an/an/an/an/an/a



Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL


Assay Description
Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT


J Med Chem 41: 2010-8 (1998)


Article DOI: 10.1021/jm970298c
BindingDB Entry DOI: 10.7270/Q2FB522Q
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50323040
PNG
(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Show SMILES CC(=NOC(=O)Nc1ccccc1)c1cccc(c1)-c1cccs1
Show InChI InChI=1S/C19H16N2O2S/c1-14(21-23-19(22)20-17-9-3-2-4-10-17)15-7-5-8-16(13-15)18-11-6-12-24-18/h2-13H,1H3,(H,20,22)
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n/an/a 1n/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells


Bioorg Med Chem Lett 20: 4406-11 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.050
BindingDB Entry DOI: 10.7270/Q24Q7V5B
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50151988
PNG
(3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pipera...)
Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1
Show InChI InChI=1S/C25H28N4O2/c26-17-19-4-6-23-22(15-19)20(18-27-23)3-1-2-8-28-9-11-29(12-10-28)21-5-7-24-25(16-21)31-14-13-30-24/h4-7,15-16,18,27H,1-3,8-14H2
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT1A expressed in CHO cell membranes assessed as increase in [35S]-GTPgammaS binding after 30 mins by liquid scintillation...


J Med Chem 61: 5822-5880 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01788
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466557
PNG
(US10800755, Example 13)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)[C@H]2C[C@@H]3CC[C@H]2O3)CC1
Show InChI InChI=1S/C20H27N3O2/c1-14-3-2-4-18(22-14)15-7-10-23(11-8-15)12-9-21-20(24)17-13-16-5-6-19(17)25-16/h2-4,7,16-17,19H,5-6,8-13H2,1H3,(H,21,24)/t16-,17-,19+/m0/s1
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n/an/a 1.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466553
PNG
(US10800755, Example 9)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H26F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-6,13H,7-12H2,1-3H3,(H,22,25)
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n/an/a 1.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM82517
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3
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n/an/a 1.10n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5-HT1A receptor expressed in CHOK1 cells incubated for 25 mins followed by addition of methiothepin by micro...


Bioorg Med Chem 27: 4163-4173 (2019)


Article DOI: 10.1016/j.bmc.2019.07.046
More data for this
Ligand-Target Pair
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