BindingDB PrimarySearch_ki

Found 50 Enz. Inhib. hit(s) with all data for entry = 50005355

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50207816(CHEMBL273094 | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...)

Ki: 5.80nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176058(2-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-...)

Ki: 6.60nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50207816(CHEMBL273094 | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...)

Ki: 8.30nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)

Ki: 12nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176058(2-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-...)

Ki: 72nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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Adenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 774nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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Adenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)

Ki: 841nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM10849(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)

Ki: 2.34E+4nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Adenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM10849(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)

Ki: 4.40E+4nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491458(CHEMBL2381774)

IC50: 30nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491458(CHEMBL2381774)

IC50: 30nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491465(CHEMBL2381773)

IC50: 39nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491465(CHEMBL2381773)

IC50: 39nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491462(CHEMBL2381761)

IC50: 41nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491462(CHEMBL2381761)

IC50: 41nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

IC50: 42nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

IC50: 42nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491457(CHEMBL2381770)

IC50: 50nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491457(CHEMBL2381770)

IC50: 50nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491459(CHEMBL2381760)

IC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491459(CHEMBL2381760)

IC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491456(CHEMBL2381757)

IC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491456(CHEMBL2381757)

IC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491448(CHEMBL2381762)

IC50: 2.63E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491448(CHEMBL2381762)

IC50: 2.63E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491455(CHEMBL2381767)

IC50: 4.37E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491455(CHEMBL2381767)

IC50: 4.37E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)

IC50: 5.25E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)

IC50: 5.25E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491454(CHEMBL2381758)

IC50: 9.12E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491454(CHEMBL2381758)

IC50: 9.12E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491464(CHEMBL2381759)

IC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491449(CHEMBL2381763)

IC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491449(CHEMBL2381763)

IC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491464(CHEMBL2381759)

IC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491460(CHEMBL2381766)

IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491461(CHEMBL2381764)

IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491452(CHEMBL2381771)

IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491463(CHEMBL2381768)

IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491463(CHEMBL2381768)

IC50: 1.10E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491460(CHEMBL2381766)

IC50: 1.20E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491452(CHEMBL2381771)

IC50: 2.57E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491461(CHEMBL2381764)

IC50: 5.50E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491450(CHEMBL2381772)

IC50: >1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491451(CHEMBL2381769)

IC50: >1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491451(CHEMBL2381769)

IC50: <1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491450(CHEMBL2381772)

IC50: <1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491453(CHEMBL2381765)

IC50: >1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Adenosine receptor A2a(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

PNG

BDBM50491453(CHEMBL2381765)

IC50: <1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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