Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50007709
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)
Affinity DataKi:  6nMAssay Description:Inhibition of human CDK2/Cyclin A expressed in baculovirus infected Sf9 insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50229973((4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(...)
Affinity DataKi:  53nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50229973((4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(...)
Affinity DataKi:  80nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50235341(CHEMBL269881 | NU-2058)
Affinity DataKi: >100nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM91749(CS16)
Affinity DataKi:  110nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50229973((4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(...)
Affinity DataKi:  396nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM8037(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 8 | 4-...)
Affinity DataKi:  396nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of GST-tagged CDK4/Cyclin D1 (unknown origin) expressed in baculovirus infected insect cells using pRb (792 to 928 residues) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM91749(CS16)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511934(CHEMBL4590821)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human CDK2/Cyclin A expressed in baculovirus infected Sf9 insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511924(CHEMBL2377864)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant CDK5 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated-histone H1 as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant CDK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated-histone H1 as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50433369(CHEMBL2377825)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511932(CHEMBL4589128)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) using histone H1 as substrate in presence of gamma[32P] ATP by phosphorimaging analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511930(CHEMBL4584344)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human CDK2/cyclin E expressed in baculovirus infected Sf21 insect cells using GST-tagged Rb protein (792 to 928 residues) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511932(CHEMBL4589128)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) using histone H1 as substrate in presence of gamma[32P] ATP by phosphorimaging analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-K(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/cyclin K expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant CDK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated-histone H1 as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM10109((3Z)-4-[(3R,4S,5R)-4-amino-3,5-dihydroxyhex-1-yn-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50433369(CHEMBL2377825)
Affinity DataIC50:  4nMAssay Description:Inhibition of GST-tagged CDK4/Cyclin D1 (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant full-length GST/His-tagged CDK5/p25 expressed in baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant CDK9 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated-histone H1 as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant GST-tagged CDK2/cyclin E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK9/human full-length untagged cyclin T1 expressed in baculovirus infected Sf21 i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511931(CHEMBL4579344)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM5670(2-amino-5-thio-substituted thiazole 47 | N-(5-{[(5...)
Affinity DataIC50:  5nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50503350(CHEMBL310840)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged CDK1/cyclin B1 (unknown origin) expressed in baculovirus expression system using histone H1 as substrate measured after 45 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/Cyclin B1 (M1 to V433 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50433369(CHEMBL2377825)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of GST-tagged CDK1/cyclin B1 (unknown origin) expressed in baculovirus expression system using histone H1 as substrate measured after 45 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK3/full-length human N-terminal GST-tagged Cyclin E expressed in baculovirus inf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50503350(CHEMBL310840)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant full-length His-tagged CDK1/cyclin B1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK3/full-length human N-terminal GST-tagged Cyclin E expressed in baculovirus inf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human N-terminal thrombin cleavage site-fused/GST-tagged CDK2 (M1 to L298 residues)/Cyclin E1 (M1 to A395 residues) express...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511929(CHEMBL4452422)
Affinity DataIC50: <10nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin) using histone-h1 as substrate measured after 10 mins in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50113281(AT-7519)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK9/human full-length untagged cyclin T1 expressed in baculovirus infected Sf21 i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511929(CHEMBL4452422)
Affinity DataIC50: <10nMAssay Description:Inhibition of CDK5/p25 (unknown origin) using histone-h1 as substrate measured after 10 mins in presence of [gamma33P]ATMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50: <10nMAssay Description:Inhibition of human recombinant full-length N-terminal His6-tagged CDK5/recombinant human full-length N-terminal GST-tagged p35 using histone H1 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDK2/Cyclin-E2(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511929(CHEMBL4452422)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant CDK2/Cyclin E2 (unknown origin) expressed in baculovirus expression system using biotinylated-histone H1 as substrate measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4/Cyclin D1 expressed in baculovirus infected Spodoptera frugiperda insect cells using pRb a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511931(CHEMBL4579344)
Affinity DataIC50:  21nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50503350(CHEMBL310840)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-tagged CDK4/Cyclin D1 (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged full length CDK7/untagged recombinant full length human Cyclin H/N-terminal GST-tagged recombi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511931(CHEMBL4579344)
Affinity DataIC50:  26nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM6683(aminoimidazo[1,2-a]pyridine deriv. 18 | {2-amino-6...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant CDK2/Cyclin E (unknown origin) expressed in baculovirus infected Sf9 insect cells using pRb (246 to 257 residues) as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 86 total ) | Next | Last >>
Jump to: