Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50010555
TargetCyclin-dependent kinase 4(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of full length GST-tagged human CDK2/Cyclin AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GST-tagged human CDK1/cyclin B expressed in SF-9 cells after 10 mins in presence of [gamma-33P]ATP by scintillation counter...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant GST-tagged human CDK2/cyclin E expressed in SF-9 cells after 10 mins in presence of [gamma-33P]ATP by scintillation counter...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length GST-tagged human CDK1/cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human CDK2/cyclin E after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human CDK2/cyclin A after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human CDK9/cyclin T after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 13(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 19(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK19 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 321nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of GSK3alpha/beta (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of CDK9 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of CDK1 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of CDK7 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataKd: 3.70E+4nMAssay Description:Binding affinity to CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataKd: 53nMAssay Description:Binding affinity to CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataKd: 5.40nMAssay Description:Binding affinity to CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Human)
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital of Zhengzhou University
Curated by ChEMBL
Affinity DataKd: 0.310nMAssay Description:Binding affinity to CDK7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to CDK8/cyclin C (unknown origin)More data for this Ligand-Target Pair