Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50017353
Affinity DataKi: 0.200nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of JAK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Competitive binding affinity to EphA4 ligand binding domain (unknown origin) using FITC-labelled EphA4 (KYLPYWPVLSSL) as a substrate assessed as inhi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human full length P13Kdelta expressed in Sf9 cells assessed as reduction in ATP-dependent phosphorylation by chromatography...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GSK3alpha (unknown origin) by ADP-glo analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MK2More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MK2More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GRK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Reversible inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Reversible inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of ASK1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of KHK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human GSK3More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK2 (unknown origin) in presence of ATP at 5 uMMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei University of Technology
Curated by ChEMBL
Hefei University of Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair