Compile Data Set for Download or QSAR
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Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50030066
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta (PDGF beta-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50:  70nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  70nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  150nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290836((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...)
Affinity DataIC50:  370nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290847(6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50:  440nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290850(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol | CHEMBL...)
Affinity DataIC50:  560nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290837(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Affinity DataIC50:  570nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290848(6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50:  600nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290844(6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline | CHEM...)
Affinity DataIC50:  700nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290853(6,7-Dimethoxy-4-phenoxy-quinoline | CHEMBL327534)
Affinity DataIC50:  760nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290841(4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline | CHE...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290846(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine | C...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290842(6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290839(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290849((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290835((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290840(4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290835((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290852(4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290845(6,7-Dimethoxy-4-m-tolyloxy-quinoline | CHEMBL98839)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290839(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290843(4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) from NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKKMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdc2More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290851(4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline | CHE...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290836((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290854(4-(2,6-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  6.93E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290849((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...)
Affinity DataIC50:  8.05E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Fibroblast growth factor receptor in NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290837(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInsulin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of insulin beta-R in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article