Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50037687
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against recombinant human KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  83nMAssay Description:Inhibitory activity against recombinant human PDGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1/2/3/4(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  92nMAssay Description:Inhibitory activity against recombinant human FGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  466nMAssay Description:Inhibitory activity against FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  545nMAssay Description:Inhibitory activity against recombinant human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibitory activity against EphB3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  9.01E+3nMAssay Description:Inhibitory activity against PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibitory activity against Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibitory activity against SGKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibitory activity against AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibitory activity against PKC alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50182212(7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibitory activity against PKC deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed