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Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50044699
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM482157(BDBM50379529 | LRRK2-IN-1 | US11370796, Compound L...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026589(CHEMBL2206014)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant LRRK2 G2019S mutant (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026589(CHEMBL2206014)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant GSK3alpha using CFFKNIVTPRTPPPSQGK-amide substrate after 60 mins incubation by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026597(CHEMBL3335345)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026584(CHEMBL3335349)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant GSK3beta using CFFKNIVTPRTPPPSQGK-amide substrate after 90 mins incubation by LANCE methodMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026584(CHEMBL3335349)
Affinity DataIC50:  64nMAssay Description:Inhibition of recombinant LRRK2 G2019S mutant (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026591(CHEMBL3335330)
Affinity DataIC50:  163nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026586(CHEMBL3335346)
Affinity DataIC50:  194nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026596(CHEMBL3335344)
Affinity DataIC50:  204nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026594(CHEMBL3335333)
Affinity DataIC50:  205nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026588(CHEMBL3335328)
Affinity DataIC50:  261nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026592(CHEMBL3335331)
Affinity DataIC50:  466nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026585(CHEMBL3335348)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026593(CHEMBL3335332)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026587(CHEMBL3335347)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026595(CHEMBL3335335)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50026590(CHEMBL3335329)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant LRRK2 (unknown origin) using gamma-32P-ATP assessed as LRRKtide substrate phosphorylation level by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed