Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 5616
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50:  780nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  920nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  1.26E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  1.35E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  7.64E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  8.36E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  9.42E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed