Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of MAPKAPK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of human MAPKAPK5 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
Affinity DataIC50: 227nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 239nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Inhibition of human MAPKAPK5 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 392nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 437nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of MK5 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 702nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 816nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 829nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 914nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PRAK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Protein kinase PRAKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged MAPKAPK5 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MK5 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of His-tagged human PRAK expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of p38-regulated activated kinase (PRAK)More data for this Ligand-Target Pair
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of MAPKAPK5 (unknown origin) in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMpH: 7.5Assay Description:The ability of compounds to inhibit activated phospho-p38alpha is evaluated using a p38alpha /MK2 and a p38alpha /PRAK cascade assay format. The kina...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human PRAKMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged MAPKAPK5 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MK5 (unknown origin)More data for this Ligand-Target Pair