Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 data for polymerid = 50007839
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50552135(CHEMBL4303210)
Affinity DataIC50:  54nMAssay Description:Inhibition of Rho-Pam3 binding to TLR1 (unknown origin)/human TLR2 expressed in HEK293 cells incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)
Affinity DataIC50: >6.50E+3nMAssay Description:Antagonist activity at TLR1 in human PBMC assessed as inhibition of Pam3CSK4-induced TNFalpha production preincubated for 30 mins followed by Pam3CSK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50463543(CHEMBL4249593)
Affinity DataIC50:  4.58E+4nMAssay Description:Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam3CSK4-stimulate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed