Affinity DataIC50: 1nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 systemMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01nMpH: 6.5Assay Description:Assays were performed at 22 °C with 2 nM MPO and 10 μM hydrogen peroxide (H2O2) in 20 mM NaH2PO4 buffer, pH 6.5 containing 140 mM NaCl, 10 mM ta...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PMN leukocytes MPO chlorination activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant MPO mediated taurine chlorination by microplate reader methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair