TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to Clostridium botulinum neurotoxin A light chain at 390 uM by isothermal titration assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 3.20nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 4.5nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 5.10nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 5.40nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 5.40nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 5.70nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 6.10nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 6.20nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 6.40nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 6.40nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 7.10nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 8.20nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 9.5nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 10.2nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain 448 residue preincubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 13.8nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 14.7nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 17.8nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 18nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 19nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 20.4nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 21.3nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 24.5nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 26nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain 448 residue coincubated with TCEP for 30 mins and TCEP absent during reaction by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Competitive inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAP-66mer (141-206aa) as substrate by FRET ...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Competitive inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAP-66mer (141-206aa) as substrate by FRET ...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 28nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 30.6nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 31.7nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 33.3nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of Clostridium botulinum truncated-BoNT/A light chain 424 residue preincubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 39.8nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/A using N(K)-acetyl)-SNKTRIDEANQRATKML-carboxamide as substrateMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 44nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain 448 residue coincubated with TCEP for 60 mins and TCEP absent during reaction by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 53nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Inhibition of Clostridium botulinum BoNT/A LC assessed as cleavage of SNAP-25 (141 to 206) after 30 mins by LC-MS analysisMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 103nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 118nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Competitive inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAP-66mer (141-206aa) as substrate by FRET ...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 157nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain 448 residue coincubated with TCEP for 30 mins and TCEP present during reaction by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Competitive inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAP-66mer (141-206aa) as substrate by FRET ...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 162nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain 448 residue coincubated with TCEP for 60 mins and TCEP present during reaction by FRET assayMore data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Lakehead University And Thunder Bay Regional Research Institute
Curated by ChEMBL
Affinity DataKi: 171nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 182nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 207nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A [1-429](Clostridium botulinum (strain Hall / ATCC 3502 / N...)
Hawaii Biotech
US Patent
Hawaii Biotech
US Patent
Affinity DataKi: 214nMAssay Description:In a 96 well, clear bottom black plate, the following was added to each well: 5 nM BoNT/A LC1-429, 28 μM substrate in 30 mM HEPES pH 7.3, 0.05 m...More data for this Ligand-Target Pair