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Found 3 Enz. Inhib. hit(s) with Target = 'Peroxiredoxin-1'
TargetPeroxiredoxin-1(Homo sapiens)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50504090(CHEMBL4092369)
Affinity DataKd:  1.83E+3nMAssay Description:Binding affinity to full-length human PRDX1 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxiredoxin-1(Homo sapiens)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50411905(CHEMBL272733)
Affinity DataKd:  2.61E+3nMAssay Description:Binding affinity to full-length human PRDX1 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxiredoxin-1(Homo sapiens)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50431029(CHEMBL574646)
Affinity DataIC50:  950nMAssay Description:Inhibition of PRDX1 in human PMA-differentiated LPS-stimulated THP1 cells assessed as reduction in NLRP3 inflammasome activation preincubated for 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed