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Found 239 Enz. Inhib. hit(s) with Target = 'Sonic hedgehog protein'
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50612865(CHEMBL5276737)
Affinity DataKd:  170nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50590850(CHEMBL5185285)
Affinity DataKd:  550nMAssay Description:Binding affinity to SHH (unknown origin) assessed as dissociation constant by calorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataKd:  570nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311519(CHEMBL1088172 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311525(CHEMBL1081726 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to SHHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to N-terminal sonic hedgehog (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to N-terminal Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311523(CHEMBL1081555 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311526((S,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataKd:  5.70E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311524(CHEMBL1079558 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  8.70E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311518(CHEMBL1087150 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataKd:  8.90E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50323698(2-((3S,6S,12S,E)-12-amino-3-methyl-5,13-dioxo-1-ox...)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to N-terminal Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311530((R,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50017345(CHEMBL3288260)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to human recombinant Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311527((S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataKd:  2.38E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50017346(CHEMBL3288258)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to human recombinant Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311529((R,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataKd:  3.82E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311520(CHEMBL1087530 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311522(CHEMBL1080649 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))TBA
LigandPNGBDBM50017347(CHEMBL3288259)
Affinity DataKd:  1.22E+5nMAssay Description:Binding affinity to human recombinant Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189251(US9173869, 5)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189252(US9173869, 6)
Affinity DataIC50: <500nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189253(US9173869, 11)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189254(US9173869, 31)
Affinity DataIC50: <1.00E+4nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189255(US9173869, 32)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189256(US9173869, 34)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189257(US9173869, 36)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189258(US9173869, 38)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189259(US9173869, 39)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189260(US9173869, 40)
Affinity DataIC50: <1.00E+4nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189261(US9173869, 41)
Affinity DataIC50: <1.00E+4nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189262(US9173869, 42)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189263(US9173869, 43)
Affinity DataIC50: <1.00E+4nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189264(US9173869, 44)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189265(US9173869, 45)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189266(US9173869, 46)
Affinity DataIC50: <500nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189267(US9173869, 47)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189268(US9173869, 48)
Affinity DataIC50: <500nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189269(US9173869, 49)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189270(US9173869, 50)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189271(US9173869, 51)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189272(US9173869, 52)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189273(US9173869, 53)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189274(US9173869, 54)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189275(US9173869, 55)
Affinity DataIC50: <5.00E+3nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSonic hedgehog protein(Mus musculus (Mouse))
Curis

US Patent
LigandPNGBDBM189276(US9173869, 56)
Affinity DataIC50: <1.00E+4nMT: 2°CAssay Description:Compounds may be tested in the "Gli-Luc" assay below, using the cell line 10T(s12), wherein the cells contain a Hedgehog-responsive reporter construc...More data for this Ligand-Target Pair
In DepthDetails US Patent
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