Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 1073
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307520((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50:  6.80E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307533((S)-1-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6-...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307522((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50:  7.10E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307523((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50:  7.00E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307524((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50:  7.30E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307525((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50:  6.60E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307526((S)-2-(N-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)...)
Affinity DataEC50:  6.60E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307527((R)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylam...)
Affinity DataEC50:  6.90E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307528((S)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylam...)
Affinity DataEC50:  6.70E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307529((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...)
Affinity DataEC50:  6.60E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307529((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...)
Affinity DataEC50:  6.70E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307531((S)-2-((3-(4-((2-amino-4-(l-hydroxyhexan-3-ylamino...)
Affinity DataEC50:  7.00E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307532((R)-1-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylamino...)
Affinity DataEC50:  6.70E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307533((S)-1-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6-...)
Affinity DataEC50:  5.70E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307520((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307521(2-((4-((2-amino-4-(butylamino)-6-methylpyrimidin-5...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307522((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307523((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307524((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307525((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307526((S)-2-(N-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307527((R)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylam...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307528((S)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylam...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307529((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307529((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307531((S)-2-((3-(4-((2-amino-4-(l-hydroxyhexan-3-ylamino...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307532((R)-1-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylamino...)
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307521(2-((4-((2-amino-4-(butylamino)-6-methylpyrimidin-5...)
Affinity DataEC50:  6.10E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent